Investigation of the Nutrient Uptake and Cell Growth Kinetics with Monod and Moser Models for Penicillium brevicompactum ATCC 16024 in Batch Bioreactor

(Received: May 11, 2011; June 13, 2011) Abstract: In the most cases of the practical fermentation processes with filamentous microorganisms, direct monitoring of the cell morphology and biomass distribution in the culture medium is not easily possible. Use of a mathematical model is a suitable way to describe the substrate uptake and cell growth behavior of these microorganisms. Penicillium brevicompactum is one of the morphologically complex filamentous fungi with different structural forms. In this work, nutrient uptake and cell growth kinetics were investigated using Monod and Moser models through batch submerged fermentation in a bench-scale stirred tank bioreactor. The experimental data were fitted with both the Monod and the Moser kinetic with a regression value of 0.87. The maximum specific growth rate and Monad's half-saturation coefficient were determined as 0.04 h and 9 g. L , 1 1